The opioid crisis only intensified as more illicit drugs entered the market. The number of deaths due to drug overdose has reached the number
record high in 2021, with more than 100,000 deaths from the ongoing epidemic, fueled by the potent synthetic narcotic fentanyl. According to the Centers for Disease Control and Prevention, the drug can be 50 times more potent than heroin and 100 times more potent than morphine. Illegal forms of fentanyl are mainly produced by drug cartels in Mexico and widespread in the US
https://www.wsj.com/articles/what-is-fentanyl-drug-opioid-health-safety-explained-11658341650 What Is Fentanyl and Why Is It So Dangerous?